Adalat CC Nifedipine
The pharmacological drug Adalat CC is used as a calcium channel blocker. It’s a powerful hypotensive and anti-anginal drug. It helps normalize blood pressure even when the values rise to critical values. Admission of the drug should be controlled by the attending physician.
Chemical structure of the active substance
The active component of the drug is Nifedipine. It’s a derivative of 1,4-dihydropyridine. The substance in its pure form is small yellow crystals. The powder isn’t soluble in water.
The drug is available as tablets for oral administration. The content of the active substance in each tablet is 30 mg.
Pharmacokinetics and pharmacodynamics
The maximum bioavailability of the active component of Adalat Medicine is 40-60%. This is enough to quickly reduce blood pressure to normal values. The maximum concentration of nifedipine is registered 30 minutes after oral administration. The hypotensive effect lasts for 4-6 hours.
Nifedipine is 90% bound to plasma proteins. The substance is excreted from the body as inactive metabolites. 80% of the spent drug leaves the body with urine, another 15% - with feces.
Mechanism of action
Adalat medicine blocks the movement of calcium through channels. Ions partially stop entering the cardiomyocytes and vascular wall smooth muscle cells through the membranes. Against the background of taking the drug, the lumen of coronary vessels expands. As a result, there is a rapid decrease in blood pressure values and a decrease in the load on the heart muscle.
Adalat CC promotes the increase in coronary blood flow, decrease of oxygen consumption, improvement of myocardial function, decrease of heart size with enlargement of connective tissue.
Indications for prescribing
Adalat drug is recommended for:
moderate to severe arterial hypertension;
List of contraindications
The list of absolute contraindications to the prescription of tablets with nifedipine in the composition includes:
hypersensitivity to the active substance or auxiliary components;
suffered myocardial infarction - allowed to take 8-10 days after the attack;
decompensated chronic heart failure;
The drug is recommended for patients over 18 years of age. The safety of treatment of children and adolescents with arterial hypertension with nifedipine-based drugs has not been studied. No data on efficacy have been presented.
Adalat CC administration may provoke temporary worsening of well-being. The list of the most common side effects includes fever; hyperemia; palpitations; preconsciousness; dizziness; migraine; tinnitus; decreased sensitivity in the fingers; tremor; constipation; urticaria.
Adalat medicine’s overdose
If the therapeutic dose is exceeded, intoxication with Adalat medicine cannot be ruled out. In moderate cases of poisoning severity arterial blood pressure is sharply reduced, bradycardia develops. In severe cases, cardiogenic shock, loss of consciousness, coma are not excluded.
What measures are taken in case of overdose: gastric lavage, sorbents, intravenous injection of calcium chloride, or calcium gluconate solutions.
Hemodialysis is not carried out due to binding to plasma proteins. To avoid intoxication, it’s recommended to observe the daily dose, especially when treating elderly patients.
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We offer Mex Post Express Shipping as an option. This option costs from $24.95 depending on the quantity of medications in your order (up to 9 medications). This option requires a customer signature on delivery. For all other locations Express Shipping is $39.95. All packages are shipped in plain packaging to guarantee your privacy. All packages are sent by parcel express mail from Mexico. Some parcels require a signature upon delivery at our discretion. There are no other handling fees, drug dispensing fees, or Mexican customs charges. If two or more people are ordering their prescription drugs from the same address at the same time, you will be billed for only one shipping charge from our Mexico pharmacy, up to our maximum order quantities limited by customs to 90 day supply. We are able to provide a tracking number on your express shipping parcels. If after 30 business days your order has not arrived, first check with your local postal office to ensure that your package is not being held for pick-up. If you still have problems, please contact us by email and we will attempt to assist you.
If no one is at home at the time of delivery, the status of you order on the Postal System will be updated to “Notice Left” which means USPS attempted to deliver your item and a notice was left because an authorized recipient was not available. You may arrange redelivery by visiting or calling 800-ASK-USPS, or may pick up the item at the Post Office indicated on the notice. If this item is unclaimed after five days then it will be returned to the sender. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).
Note that on Holidays season, the Mexican Postal, USA and other countries will be extra busy; therefore a delay is expected in packages shipped during this season. You will need to consider as well the Mexican holidays. We appreciate your understanding, our customer service will be happy to assist you and available to inform you the latest status on your existing order shipped, you can always contact us at Toll Free number or email address.
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How to find the online pharmacy drug you need.
There are many more medications available in Mexico that are not listed on our website. If you can’t find the Mexican drug or medication you require, please contact us and we may be able to help. Some products are listed only in a single dosage size or medicine type, but may be available in other dosages and forms. Our experienced Mexican pharmacy Pharmacists will do their best to accommodate your requirements. Please always specify the chemical name of the medication (and any applicable brand name) with all inquiries. Please feel free to ask about ANY drug. We will reply promptly to your request.
What you should know about brand and generic drug alternates.
Prescription drugs are a costly medical expense, especially for the elderly, those who are chronically ill and those with no or minimal drug coverage on their Health Insurance. However, each state in America has a law that allows pharmacists to substitute less expensive generic drugs for many brand name products. Depending on your prescription needs, your savings could be very significant. Before you talk with your doctor or pharmacist about switching, there are things you should know about generic drugs.
What is the difference between a generic and brand name drug?
Nothing except for the name, packaging, and the price, a generic drug is called by its chemical name; manufacturers assign their own brand name. The generic products have the same ingredients. Standard practice and most state laws require that a generic drug be generically equivalent to its brand name counterpart. That is, it must have the same active ingredients, strength, and dosage form, be it a pill, liquid, or injection. The generic drug also must be therapeutically equivalent. It must be the same drug chemically and have the same medical effect.
Do all drugs have generic equivalents?
No. Some drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.
Will my doctor automatically prescribe generic drugs?
It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate or to define the chemical name for the prescription. This will ensure you are purchasing the correct Mexico drug. Generic products will be as effective and less costly. Or, you can order only brand name products if you wish. www.MedsMex.com.com Mexico pharmacy offers a wide selection of both Brand Name & Generic Mexico medicine. Our Mexican generic drugs are of the highest quality, selected only from the most reputable manufacturers, and are safe to replace brand name medications costing much more.
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